The Italian defender returns to his homeland for the Group F encounter, having helped Nicky Butt's side defeat the Bianconeri youngsters 4-1 in the previous outing in the competition.
The Reds are in fine form, topping the table with three wins out of three, but this will represent a stern test against a Juve team that will be keen to exact revenge for the Leigh Sports Village reverse, when they finished the game with 10 men.
In an exclusive interview with MUTV, the centre-back explained that it will be a sentimental occasion when he turns out again against the club he admired as a child.